New directions in research on information requirements analysis: the language connection

This paper outlines the basic theoretical assumptions of language analysis and then proposed a new approach called discourse analysis. The theoretical foundations of discourse analysis are Wittgenstein's theory of language games and Harbermas' social action types. It has potential applications to information requirements analysis and research in organisational theory

Responsive Production in Manufacturing: A Modular Architecture

[EN] This paper proposes an architecture aiming at promoting the convergence of the physical and digital worlds, through CPS and IoT technologies, to accommodate more customized and higher quality products following Industry 4.0 concepts. The architecture combines concepts such as cyber-physical systems, decentralization, modularity and scalability aiming at responsive production. Combining these aspects with virtualization, contextualization, modeling and simulation capabilities it will enable self-adaptation, situational awareness and decentralized decision-making to answer dynamic market demands and support the design and reconfiguration of the manufacturing enterprise.The research leading to these results has received funding from the European Union H2020 project C2 NET (FoF-01-2014) nr 636909.Marques, M.; Agostinho, C.; Zacharewicz, G.; Poler, R.; Jardim-Goncalves, R. (2018). Responsive Production in Manufacturing: A Modular Architecture. 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Business Development Through Digital Transformation: The Evolution of Amazon.Com

Since 1995, when the first book was sold as an online bookstore, Amazon has continued to evolve turning to a provider of cloud computing services and a publisher. The aim of the present paper is to investigate this evolution focusing on the concept of platform and the concept of infrastructure as metaphors of the business/environment relationship and of the reframing of business sectors. In the case in question, an overlapping between the concept of platform proposed and the technological platform emerges so that it has become the backbone on which Amazon\u2019s businesses run. On the other hand, the concept of infrastructure outlines an environment in which customers can turn into suppliers and also into partners

Accessory Atrioventricular Myocardial Pathways in Mouse Heart Development: Substrate for Supraventricular Tachycardias

Atrioventricular reentry tachycardia (AVRT) requiring an accessory atrioventricular pathway (AP) is the most common type of arrhythmia in the perinatal period. The etiology of these arrhythmias is not fully understood as well as their capability to dissipate spontaneously in the first year of life. Temporary presence of APs during annulus fibrosus development might cause this specific type of arrhythmias. To study the presence of APs, electrophysiological recordings of ventricular activation patterns and immunohistochemical analyses with antibodies specifically against atrial myosin light chain 2 (MLC-2a), Periostin, Nkx2.5, and Connexin-43 were performed in embryonic mouse hearts ranging from 11.5 to 18.5 days post-conception (dpc). The electrophysiological recordings revealed the presence of functional APs in early (13.5-15.5 dpc) and late (16.5-18.5 dpc) postseptated stages of mouse heart development. These APs stained positive for MLC-2a and Nkx2.5 and negative for Periostin and Connexin-43. Longitudinal analyses showed that APs gradually decreased in number (p = 0.003) and size (p = 0.035) at subsequent developmental stages (13.5-18.5 dpc). Expression of periostin was observed in the developing annulus fibrosus, adjacent to APs and other locations where formation of fibrous tissue is essential. We conclude that functional APs are present during normal mouse heart development. These APs can serve as transient substrate for AVRTs in the perinatal period of developmen